Emergence of SARS-like Coronavirus Poses New Challenge in China (2020/01/30)

Recently, the emergence of African swine fever virus in China has raised great concern in this journal.1,2 The epidemic is not over yet, outbreak of a new SARS-like Coronavirus in Wuhan at the end of 2019 poses new public health challenges in China. Coronaviruses are a large family of viruses that cause respiratory illnesses. Although Coronaviruses (CoVs) have been known for decades, they did not raise great attention in human medicine until the outbreaks of Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS).3 SARS-CoV first emerged in November 2002 in Guangdong province of Southern China and then rapidly spread to 29 countries and regions, infecting over 8000 individuals with a death toll of nearly 800.3 Ten years after the SARS, MERS emerged in 2012, have caused 2494 human infections with 858 deaths (as of November 2019) and remains a disease of global, and particularly Middle Eastern, public health concern. In 2017, a novel HKU2-related bat coronavirus, swine acute diarrhea syndrome coronavirus (SADS-CoV), caused the death of 24,693 piglets,4,5 raising further concern about these coronavirus. In December 2019, a new coronavirus (2019-nCoV), which is about 70% similar to SARS-Cov, was discovered in the central Chinese city of Wuhan, with 545 cases in 25 provinces being diagnosed (Fig. 1A, January 22, 2020). According to the World Health Organization (https://www.who.int), in addition to mainland China, this virus has also been detected in Japan, Thailand, Republic of Korea and the United States in travelers from Wuhan. The number of confirmed cases has been gradually increasing (Fig. 1B), which might be partially due to recent the establishment of relevant detection methods, but, at the same time, could signal that there could be a quick expansion of the epidemic.

Author: Ruichen Wang, Xu Zhang, David M.Irwin, et al.

Link: https://www.sciencedirect.com/science/article/pii/S0163445320300578?via%3Dihub